thiazolidinedione


thiazolidinedione
thi·a·zol·i·dine·di·one .thī-ə-.zō-lə-.dēn-'dī-.ōn n any of a class of drugs (as pioglitazone and rosiglitazone) that are thiazolidine derivatives used to reduce insulin resistance in the treatment of type 2 diabetes

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thi·a·zol·i·dine·di·one (TZD) (thi″ə-zōl″ə-dēn-diґōn) any of a group of structurally related oral antihyperglycemic agents that increase insulin-stimulated glucose uptake by skeletal muscle cells, reducing insulin resistance in peripheral tissues, and decrease lipolysis in adipocytes.

Medical dictionary. 2011.

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  • Rosiglitazone — drugbox IUPAC name = 5 ((4 (2 (methyl 2 pyridinylamino) ethoxy)phenyl)methyl) 2,4 thiazolidinedione width = 95 CAS number = 122320 73 4 ATC prefix = A10 ATC suffix = BG02 PubChem = 77999 DrugBank = APRD00403 C = 18 | H = 19 | N = 3 | O = 3 | S =… …   Wikipedia

  • Ciglitazone — Systematic (IUPAC) name 5 {4 [(1 methylcyclohexyl)methoxy]benzyl} 1,3 thiazolidine 2,4 dione Clinical data Pregnancy cat …   Wikipedia

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  • Pioglitazone — Systematic (IUPAC) name (RS) 5 (4 [2 (5 ethylpyridin 2 yl)ethoxy]benzyl)thiazolidine 2,4 dione Clinical data …   Wikipedia