Beta blocker


Beta blocker
A class of drugs that block beta-adrenergic substances such as adrenaline (epinephrine), a key agent in the "sympathetic" portion of the autonomic (involuntary) nervous system. By blocking the action of the sympathetic nervous system on the heart, beta blockers relieve stress on the heart. They slow the heart beat, lessen the force with which the heart muscle contracts and reduce blood vessel contraction in the heart, brain, and throughout the body. Beta blockers can serve to treat abnormal heart rhythms (cardiac arrhythmias). They are used specifically to prevent abnormally fast heart rates (tachycardias) or irregular heart rhythms such as premature ventricular beats. Since beta blockers reduce the demand of the heart muscle for oxygen and the chest pain of angina pectoris occurs when the oxygen demand of the heart exceeds the supply, beta blockers can be useful in treating angina. They have also become an important drug in improving survival after a person has had a heart attack. Thanks to their effect on blood vessels, beta blockers can lower the blood pressure and be of value in the treatment of hypertension. Other uses for beta blockers include the prevention of migraine headaches and the treatment of certain types of tremors (familial or hereditary essential tremors). The beta blockers (with brand names) include acebutolol (Sectral), atenolol (Tenormin), bisoprolol (Zebeta), metoprol (Lopressor, Lopressor LA, Toprol XL), nadolol (Corgard), and timolol (Blocadren). Beta blockers are also available in combination with a diuretic as, for example, with bisoprolol and hydrochlorothiazide (Ziac). Beta blockers reduce the pressure within the eye (the intraocular pressure), probably by reducing the production of the liquid (aqueous humor) within the eye, and so are used to lessen the risk of damage to the optic nerve and loss of vision in glaucoma. Beta blocker preparations for this purpose include timolol ophthalmic solution (Timoptic) and betaxolol

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a drug that prevents stimulation of the beta-adrenergic receptors at the nerve endings of the sympathetic nervous system. There are two kinds of beta receptors: beta 1 receptors are in the heart, and blockade causes a decrease in heart rate and force; beta 2 receptors are in the airways and the arteries, in both of which blockade causes constriction. Beta blockers include acebutolol, betaxolol, bisoprolol, oxprenolol, propranolol, and sotalol; they are used to control abnormal heart rhythms, to treat angina, and to reduce high blood pressure. Beta blockers that block both beta 1 and beta 2 receptor sites cause constriction of air passages in the lungs, and care has to be taken with the use of these drugs in patients with any bronchial conditions. Other beta blockers are relatively selective for the heart (cardioselective) and are less likely to constrict the airways. Some beta blockers (e.g. carteolol, levobunolol, and timolol) reduce the production of aqueous humour and therefore the pressure inside the eye; they are taken as eye drops in the treatment of glaucoma.

Medical dictionary. 2011.

Look at other dictionaries:

  • Beta blocker — Beta blockers Drug class Skeletal formula of propranolol, the first clinically successful beta blocker ATC code C07 …   Wikipedia

  • beta blocker — beta blocking, adj. Pharm. any of various substances that interfere with the action of the beta receptors: used primarily to reduce the heart rate or force in the prevention, management, or treatment of angina, hypertension, or arrythmias. Also,… …   Universalium

  • beta blocker — n. any of a class of drugs used to control heartbeat, relieve angina pectoris, treat hypertension, etc. by blocking the nerve impulses that normally excite the beta receptors …   English World dictionary

  • beta blocker — ► NOUN ▪ a drug which prevents increased cardiac action, used to treat angina and reduce high blood pressure …   English terms dictionary

  • Beta-Blocker — Betablocker (Syn.: Beta Rezeptorenblocker, Beta Adrenozeptorenblocker, β Blocker) ist in der Medizin ein Sammelbegriff für eine Reihe ähnlich wirkender Arzneistoffe, die im Körper an β Rezeptoren als inverse Agonisten wirken und so die Wirkung… …   Deutsch Wikipedia

  • Beta Blocker — Betablocker (Syn.: Beta Rezeptorenblocker, Beta Adrenozeptorenblocker, β Blocker) ist in der Medizin ein Sammelbegriff für eine Reihe ähnlich wirkender Arzneistoffe, die im Körper an β Rezeptoren als inverse Agonisten wirken und so die Wirkung… …   Deutsch Wikipedia

  • beta blocker — noun any of various drugs used in treating hypertension or arrhythmia; decreases force and rate of heart contractions by blocking beta adrenergic receptors of the autonomic nervous system • Syn: ↑beta blocking agent, ↑beta adrenergic blocker,… …   Useful english dictionary

  • beta-blocker — ˈ ̷ ̷  ̷ ̷ ˈ ̷ ̷  ̷ ̷ noun : any of a group of drugs (as propranolol) that combine with and block the activity of a beta receptor so as to decrease the heart rate and force of contractions and to lower high blood pressure and that are used… …   Useful english dictionary

  • beta-blocker — UK [ˈbiːtə ˌblɒkə(r)] / US [ˈbeɪtə ˌblɒkər] / US [ˈbɪtə ˌblɑkər] noun [countable] Word forms beta blocker : singular beta blocker plural beta blockers medical a drug that makes your heart work more slowly, used for treating high blood pressure …   English dictionary

  • beta blocker — [[t]bi͟ːtə blɒkə(r), AM be͟ɪtə [/t]] beta blockers N COUNT A beta blocker is a drug which is used to treat people who have high blood pressure or heart problems …   English dictionary


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