- tras·tu·zu·mab .tras-'tü-zü-.mab n a genetically engineered monoclonal antibody that is administered by injection to slow or inhibit tumor growth in some advanced breast cancers by blocking a cell membrane receptor which receives signals promoting cancer cell growth see herceptin
* * *n.a monoclonal antibody used to treat types of breast cancer that are positive for HER2: the drug binds to these receptors on the tumour. It is administered by intravenous infusion; side-effects include chills, fever, and allergic reactions. Trade name: Herceptin.
* * *tras·tuz·u·mab (tras-tuzґu-mab) a recombinant DNA-derived humanized monoclonal antibody that binds to human growth factor receptor 2 (HER2), a protein overexpressed in some breast cancers; used as an antineoplastic in the treatment of metastatic breast cancer with overexpression of HER2, administered intravenously.
Medical dictionary. 2011.