voltage clamp

voltage clamp
voltage clamp n stabilization of a membrane potential by depolarization and maintenance at a given potential by means of an electric current from a source outside the living system esp. in order to study the flow of potassium and sodium ions independently of the effects of changes in the membrane potential
voltage clamp vt

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an electronic technique employing the feedback principle to impose a fixed potential difference across a cell membrane; used in the study of ion channels. Voltage across the membrane is fixed at a set level and the current changes to counterbalance any induced flow of ions; the current change is a measure of the change in conductance of the membrane for one or more specific ions.

Medical dictionary. 2011.

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