Waterhouse-Friderichsen syndrome

Waterhouse-Friderichsen syndrome
Wa·ter·house-Frid·er·ich·sen syndrome 'wȯt-ər-.hau̇s-'frid-(ə-)rik-sən- n acute and severe meningococcemia with hemorrhage into the adrenal glands
Waterhouse Rupert (1873-1958)
British physician , and
Friderichsen Carl (1886-1979)
Danish physician. Waterhouse described in 1911 a syndrome of acute collapse associated with hemorrhages in the adrenal glands, usually observed in severe cases of meningitis caused by the meningococcus. Friderichsen published his own independent description of the syndrome in 1918.

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acute haemorrhage in the adrenal glands with haemorrhage into the skin associated with the sudden onset of acute bacteraemic shock. It is usually caused by meningococcal septicaemia (see meningitis).
R. Waterhouse (1873-1958), British physician; C. Friderichsen (20th century), Danish physician

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a fulminating complication of meningococcemia, with bilateral adrenal hemorrhages, characterized by sudden onset and short course, cyanosis with petechial hemorrhages of the skin and mucous membranes, fever, and hypotension that can lead to shock and coma.

Medical dictionary. 2011.

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  • Waterhouse-Friderichsen syndrome — ▪ pathology       a rare type of septicemia (blood poisoning) of rapid and severe onset, marked by fever, collapse and sometimes coma, hemorrhage from skin and mucous membranes, and severe bilateral hemorrhage of the adrenal cortical tissue. The… …   Universalium

  • Waterhouse-Friderichsen syndrome — noun syndrome associated with bacterial meningitis; marked by sudden high fever and skin discoloration and petechiae with hemorrhage into the adrenal glands and cardiovascular collapse • Hypernyms: ↑syndrome * * * ˈwȯ]d.ə(r)ˌhau̇ˈsfrid(ə)riksən …   Useful english dictionary

  • Waterhouse-Friderichsen syndrome — acute haemorrhage in the adrenal glands with haemorrhage into the skin associated with the sudden onset of acute bacteraemic shock. It is usually caused by meningococcal septicaemia (see meningitis) [Waterhouse (1873–1958), British physician; C.… …   The new mediacal dictionary

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  • Friderichsen-Waterhouse syndrome — Frid·er·ich·sen Wa·ter·house syndrome (fridґrik sən wawґtər hous) [Carl Friderichsen, Danish pediatrician, 20th century; Rupert Waterhouse, British physician, 1873–1958] Waterhouse Friderichsen syndrome …   Medical dictionary

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  • syndrome — The aggregate of symptoms and signs associated with any morbid process, and constituting together the picture of the disease. SEE ALSO: disease. [G. s., a running together, tumultuous concourse; (in med.) a concurrence of symptoms, fr. syn,… …   Medical dictionary

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