zinc finger

zinc finger
zinc finger n any of a class of proteins that typically possess tandem repeats of fingerlike loops of amino acids with each loop containing a zinc-binding site at its base consisting of two molecules of cysteine and two molecules of histidine and that regulates transcription by binding to specific regions of a gene's DNA also one of the fingerlike amino acid loops of such a protein

* * *

see under protein.

Medical dictionary. 2011.

Игры ⚽ Поможем написать реферат

Look at other dictionaries:

  • zinc finger —  Zinc Finger  Цинковый палец   Одна из основных групп белков, связывающих ДНК. Являются регуляторами транскрипции, содержат характерный домен, который включает 2 цистеиновых и 2 гистидиновых остатков. Эти аминокислоты взаимодействуют с ионом… …   Толковый англо-русский словарь по нанотехнологии. - М.

  • Zinc finger — A zinc finger is a large superfamily of protein domains that can bind to DNA. A zinc finger consists of two antiparallel beta; strands, and an α helix. The zinc ion is crucial for the stability of this domain type in the absence of the metal ion… …   Wikipedia

  • zinc finger — A motif associated with DNA binding proteins. A loop of 12 amino acids contains either 2 cysteine and 2 histidine groups (a cysteine histidine zinc finger), or 4 cysteines (a cysteine cysteine zinc finger), that directly coordinate a zinc atom.… …   Dictionary of molecular biology

  • Zinc finger nuclease — Zinc finger nucleases (ZFNs) are artificial restriction enzymes generated by fusing a zinc finger DNA binding domain to a DNA cleavage domain. Zinc finger domains can be engineered to target desired DNA sequences and this enables zinc finger… …   Wikipedia

  • Zinc finger chimera — Zinc finger protein chimera are chimeric proteins composed of a DNA binding zinc finger protein domain and another domain through which the protein exerts its effect. The effector domain may be a transcriptional activator (A) or repressor… …   Wikipedia

  • Zinc finger and BTB domain-containing protein 16 — Zinc finger and BTB domain containing 16, also known as ZBTB16, is a human gene. PBB Summary section title = summary text = This gene is a member of the Krueppel C2H2 type zinc finger protein family and encodes a zinc finger transcription factor… …   Wikipedia

  • Zinc finger protein transcription factor — Zinc finger protein transcription factors or ZFP TFs, consisting of activators and repressors are transcription factors composed of a zinc finger protein domain (ZFP) and any of a variety of transcription factor effector domains which exert their …   Wikipedia

  • Zinc finger protein 165 — Zinc finger protein 165, also known as ZNF165, is a human gene.cite web | title = Entrez Gene: ZNF165 zinc finger protein 165| url = http://www.ncbi.nlm.nih.gov/sites/entrez?Db=gene Cmd=ShowDetailView TermToSearch=7718| accessdate = ] PBB Summary …   Wikipedia

  • Zinc finger inhibitor — Zinc finger inhibition is the process by which the synthesis of zinc fingers is blocked. Zinc finger inhibitors have been tested for their efficacy in treating AIDS and HIV …   Wikipedia

  • zinc finger proteins — zinc finger proteins. См. белки цинковые пальцы. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

Share the article and excerpts

Direct link
Do a right-click on the link above
and select “Copy Link”