Human Genome Project

Human Genome Project
a massive international research project to elucidate the entire sequence of genes on all the human chromosomes. The human genome comprises some 3000 million nucleotide base pairs (see DNA) forming about 30,000 genes, distributed between 23 pairs of chromosomes. The sequence of these bases, along the length of each chromosome, is currently being determined in several centres in different parts of the world; a first draft of the sequence was published in 2001. The Human Genome Project is by far the most ambitious biological research programme of all time. Beginning in 1988, it is scheduled to last for 15 years. Knowledge of the entire human genome will be of incalculable value to medicine and human biology. It has already resulted in the identification of the genes associated with many hereditary disorders and revealed the existence of a genetic basis or component for many other diseases not previously known to have one. Theoretically, this would enable the development of drugs to alleviate conditions caused by deficiency of specific proteins and the large-scale genetic screening of populations known to be susceptible to particular disorders.

Medical dictionary. 2011.

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  • Human Genome Project — Hu′man Ge′nome Proj ect n. gen a scientific project to identify both the genes and the entire sequence of DNA base pairs that make up the human genome • Etymology: 1985–90 …   From formal English to slang

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