Romaña's sign

Romaña's sign
an early clinical sign of Chagas' disease, appearing some three weeks after infection. There is considerable swelling of the eyelids of one or both eyes. This may be due to the presence of the parasites causing the disease but it may also be an allergic reaction to the repeated bites of their insect carriers.
C. Romaña (20th century), Brazilian physician

Medical dictionary. 2011.

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