- pl. n.a group of sympathomimetic drugs that have a marked stimulant action on the central nervous system, alleviating fatigue and producing a feeling of mental alertness and well-being. Dexamfetamine (dexamphetamine; Dexedrine) is used in the treatment of narcolepsy and in selected cases of attention-deficit/hyperactivity disorder in children. It is administered by mouth; side-effects include insomnia and restlessness. tolerance to amphetamines develops rapidly, and prolonged use may lead to dependence; these drugs should not be used to treat depressive illness or obesity. See also methylphenidate.
Medical dictionary. 2011.