bile-acid sequestrant

bile-acid sequestrant
a drug that binds to bile acids, forming a complex that is excreted in the faeces. Bile acids are formed in the liver from cholesterol and the effect of loss of bile acids is a reduction in total body cholesterol and a decrease in low-density lipoprotein serum levels. These drugs, which include colestyramine and colestipol, are used to treat patients with abnormally high blood cholesterol levels who are liable to develop coronary heart disease.

Medical dictionary. 2011.

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  • Bile acid sequestrant — The bile acid sequestrants are a group of medications used for binding certain components of bile in the gastrointestinal tract. They disrupt the enterohepatic circulation of bile acids by sequestering them and preventing their reabsorption from… …   Wikipedia

  • bile-acid sequestrant — a drug that binds to bile acids, forming a complex that is excreted in the faeces. Bile acids are formed in the liver from cholesterol and the effect of loss of bile acids is a reduction in total body cholesterol and a decrease in low density… …   The new mediacal dictionary

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