calcium antagonist

calcium antagonist
a drug that inhibits the influx of calcium ions into cardiac and smooth-muscle cells; it therefore reduces the strength of heart-muscle contraction, reduces conduction of impulses in the heart, and causes vasodilatation. Calcium antagonists include amlodipine, diltiazem, nicardipine, nifedipine, and verapamil, which are used to treat angina and high blood pressure.

Medical dictionary. 2011.

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