leflunomide

leflunomide
n.
an immunosuppressant drug used to treat rheumatoid arthritis that has not responded to methotrexate or other antirheumatic drugs. Leflunomide is administered by mouth and side-effects, including blood disorders caused by impairment of bone-marrow function, may be severe. Trade name: Arava.

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le·flu·no·mide (lə-flooґno-mīd) an immunomodulator that inhibits pyrimidine synthesis, used as a disease-modifying antirheumatic drug in treatment of rheumatoid arthritis; administered orally.

Medical dictionary. 2011.

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Look at other dictionaries:

  • Leflunomide — drugbox IUPAC name = 5 methyl N [4 (trifluoromethyl) phenyl] isoxazole 4 carboxamide CAS number = 75706 12 6 ATC prefix = L04 ATC suffix = AA13 ATC supplemental = PubChem = 3899 DrugBank = APRD00205 C=12 | H=9 | F=3 | N=2 | O=2 molecular weight …   Wikipedia

  • leflunomide — n. an immunosuppressant drug used to treat rheumatoid and psoriatic arthritis that have not responded to methotrexate or other disease modifying antirheumatic drugs. Leflunomide is administered by mouth and side effects, including blood disorders …   The new mediacal dictionary

  • leflunomide — noun An inhibitor of pyrimidine synthesis, used to treat some forms of arthritis …   Wiktionary

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  • leflunomide — noun an anti TNF compound (trade name Arava) that is given orally; can slow the progression of rheumatoid arthritis by slowing the proliferation of white blood cells which reduces inflammation in the synovium • Syn: ↑Arava • Usage Domain: ↑trade… …   Useful english dictionary

  • Leflunomid — Strukturformel Allgemeines Freiname Leflunomid Andere Namen …   Deutsch Wikipedia

  • Teriflunomide — Drugbox IUPAC name = (Z) 2 Cyano 3 hydroxy N [4 (trifluoromethyl)phenyl] 2 butenamide CAS number = 163451 81 8 CAS supplemental = ATC prefix = ATC suffix = ATC supplemental = PubChem = 5479847 DrugBank = chemical formula = C=12 | H=9 | F=3 | N=2… …   Wikipedia

  • Rheumatoid arthritis — Classification and external resources A hand affected by rheumatoid arthritis ICD 10 M …   Wikipedia

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  • Dihydroorotate dehydrogenase — Dihydroorotate oxidase Identifiers EC number 1.3.3.1 CAS number 9029 03 2 …   Wikipedia

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