acyl-CoA dehydrogenase

acyl-CoA dehydrogenase
ac·yl-CoA de·hy·dro·gen·ase (aґsəl ko-aґ de-hiґdro-jən-ās) [EC 1.3.99.3] any of several enzymes of the oxidoreductase class that catalyze the oxidation of acyl coenzyme A thioesters to the enoyl coenzyme A form, using a flavin electron acceptor. The reaction is a step in the degradation of fatty acids and the trans isomer of enoyl coenzyme A is formed exclusively. Individual enzymes are specific for certain ranges of acyl chain lengths. See also electron transfer flavoprotein, under flavoprotein.

Medical dictionary. 2011.

См. также в других словарях:

  • Acyl CoA dehydrogenase — is the enzyme used to catalyze the first step of β oxidation in Fatty acid metabolism. ReactionThe following reaction is the oxidation of the fatty acid by FAD.The enzyme catalyzes the formation of a double bond between the C 2 and C 3. The end… …   Wikipedia

  • Acyl-CoA dehydrogenase (NADP+) — In enzymology, an acyl CoA dehydrogenase (NADP+) (EC number|1.3.1.8) is an enzyme that catalyzes the chemical reaction:acyl CoA + NADP+ ightleftharpoons 2,3 dehydroacyl CoA + NADPH + H+Thus, the two substrates of this enzyme are acyl CoA and… …   Wikipedia

  • Medium-Chain-Acyl-CoA-Dehydrogenase-Mangel — Klassifikation nach ICD 10 E71.3 Störungen des Fettsäurestoffwechsels …   Deutsch Wikipedia

  • Long-chain-acyl-CoA dehydrogenase — In enzymology, a long chain acyl CoA dehydrogenase (EC number|1.3.99.13) is an enzyme that catalyzes the chemical reaction:acyl CoA + acceptor ightleftharpoons 2,3 dehydroacyl CoA + reduced acceptorThus, the two substrates of this enzyme are acyl …   Wikipedia

  • long-chain acyl-CoA dehydrogenase — See acyl CoA dehydrogenase (NADPH) …   Medical dictionary

  • medium-chain acyl-CoA dehydrogenase — See acyl CoA dehydrogenase (NADPH) …   Medical dictionary

  • short-chain acyl-CoA dehydrogenase — See acyl CoA dehydrogenase (NADPH) …   Medical dictionary

  • long-chain acyl-CoA dehydrogenase (LCAD) deficiency — a defect in mitochondrial beta oxidation due to a mutation in the gene (locus: 2q34 q35) encoding the acyl CoA dehydrogenase that acts on long chain length fatty acids. It is clinically similar to MCAD deficiency, but urinary excretion is of long …   Medical dictionary

  • medium-chain acyl-CoA dehydrogenase (MCAD) deficiency — a defect in mitochondrial beta oxidation due to a mutation in the gene (locus: 1p31) encoding acyl CoA dehydrogenase that acts on medium chain length fatty acids. It is characterized by recurring episodes of hypoglycemia, vomiting, and lethargy,… …   Medical dictionary

  • short-chain acyl-CoA dehydrogenase (SCAD) deficiency — a defect in mitochondrial beta oxidation due to a mutation in the gene (locus: 12q22 qter) encoding the acyl CoA dehydrogenase that acts on short chain length fatty acids. Clinical presentation is variable, but myopathy and abnormalities of… …   Medical dictionary


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