Freund adjuvant

Freund adjuvant
a water-in-oil emulsion incorporating antigen, in the aqueous phase, into lightweight paraffin oil with the aid of an emulsifying agent. On injection, this mixture (Freund incomplete a.) induces strong persistent antibody formation. The addition of killed, dried mycobacteria, e.g., Mycobacterium butyricum, to the oil phase (Freund complete a.) elicits cell-mediated immunity (delayed hypersensitivity), as well as humoral antibody formation.

Medical dictionary. 2011.

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  • Freund adjuvant — Freund adjuvant. См. адъювант Фрейнда. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • Freund adjuvant — (froind) [Jules Thomas Freund, Hungarian born bacteriologist in the United States, 1890–1960] see under adjuvant …   Medical dictionary

  • Freund's adjuvant — is an antigen solution emulsified in mineral oil, used as an immunopotentiator (booster of the immune system). FormsThe so called complete form (CFA) is composed of inactivated and dried mycobacteria, usually Mycobacterium tuberculosis (the… …   Wikipedia

  • Freund's adjuvant — frȯin(d)z , frȯin(t)s n any of several oil and water emulsions that contain antigens and are used to stimulate antibody production in experimental animals Freund frȯind Jules Thomas (1890 1960) American immunologist. Freund was a pioneer in… …   Medical dictionary

  • Freund — (German for friend ) is a surname and may refer to:* Ernst Freund * Gisèle Freund (1912 2000), photographer * Jules T. Freund * Karl Freund * Kurt Freund * Michael Freund * Steffen Freund, German soccer player * Tom Freund * Wilhelm Freund (1806… …   Wikipedia

  • Freund'sadjuvant — Freund s adjuvant (froindz) n. A substance consisting of killed microorganisms, such as mycobacteria, in an oil and water emulsion that is administered to induce and enhance the formation of antibodies.   [After Jules T. Freund (1890 1960),… …   Universalium

  • Adjuvant immunologique — Dans le domaine médical et vétérinaire, un adjuvant[1] immunologique (appelé aussi adjuvant vaccinal, immunoactivateur, immunoadjuvant, immunopotentialisateur, immunostimulant) ou immunomodulateur (ce terme est plus précis que celui d adjuvant… …   Wikipédia en Français

  • Adjuvant — The Latin “adjuvans” means to help, particularly to reach a goal. Adjuvant therapy for cancer is surgery followed by chemotherapy or radiation to help decrease the risk of the cancer recurring (coming back). An adjuvant is a substance that helps… …   Medical dictionary

  • freund's adjuvant — ˈfrȯin(d)z noun Usage: usually capitalized F Etymology: after Jules T. Freund b1890 American immunologist : any of various substances (as lanolin, paraffin oil, or killed tubercle bacilli) added to an antigen to enhance its antigenicity * * *… …   Useful english dictionary

  • Freund's adjuvant — /froyndz/, Immunol. a water in oil emulsion injected with immunogen (Freund s incomplete adjuvant) or with immunogen and killed mycobacteria (Freund s complete adjuvant) to enhance the immune response to the immunogen. [1945 50; after Jules… …   Universalium

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