calcium channel blocking agent


calcium channel blocking agent
any of a group of drugs that inhibit the entry of calcium into cells or inhibit the mobilization of calcium from intracellular stores, resulting in slowing of atrioventricular and sinoatrial conduction and relaxation of arterial smooth and cardiac muscle; used in the treatment of angina, cardiac arrhythmias, and hypertension.

Medical dictionary. 2011.

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  • calcium channel blocker — n any of a class of drugs (as verapamil) that prevent or slow the influx of calcium ions into smooth muscle cells esp. of the heart and that are used esp. to treat some forms of angina pectoris and some cardiac arrhythmias called also calcium… …   Medical dictionary

  • agent — 1. An active force or substance capable of producing an effect. For agents not listed here, see the specific name. 2. A disease, a factor such as a microorganism, chemical substance, or a form of radiation the presence or …   Medical dictionary

  • Neuromuscular-blocking drug — Global view of a neuromuscular junction: 1. Axon 2. Motor end plate 3. Muscle fiber 4. Myofibril …   Wikipedia

  • Antiarrhythmic agent — The cardiac action potential Antiarrhythmic agents are a group of pharmaceuticals that are used to suppress abnormal rhythms of the heart (cardiac arrhythmias), such as atrial fibrillation, atrial flutter, ventricular tachycardia, and ventricular …   Wikipedia

  • nifedipine — A calcium channel blocking agent of the dihydropyridine type; coronary vasodilator. * * * ni·fed·i·pine nī fed ə .pēn n a calcium channel blocker C17H18N2O6 that is a coronary vasodilator used esp. in the treatment of angina pectoris see ADALAT …   Medical dictionary

  • Antagonist — In biochemistry, an antagonist acts against and blocks an action. For example, insulin lowers the level of glucose (sugar) in the blood, whereas another hormone called glucagon raises it; therefore, insulin and glucagon are antagonists. An… …   Medical dictionary

  • felodipine — A calcium blocking agent of the dihydropyridine class resembling nifedipine. * * * fe·lo·di·pine fə lō də .pēn, .pīn n a calcium channel blocker C18H19Cl2NO4 used esp. in the treatment of hypertension * * * fe·lo·di·pine (fə loґdĭ… …   Medical dictionary

  • Nicardipine — Systematic (IUPAC) name 2 [benzyl(methyl)amino]ethyl methyl 2,6 dimethyl 4 (3 nitrophenyl) 1,4 dihydropyridine 3,5 dicarboxylate Clinical data AHFS/ …   Wikipedia

  • nimodipine — A calcium channel blocking drug of the dihydropyridine series used as a vasodilator. * * * ni·mo·di·pine ni mōd ə .pēn n a calcium channel blocker C21H26N2O7 * * * ni·mo·di·pine (ni moґdĭ pēn) [USP] a calcium channel blocking agent …   Medical dictionary

  • diltiazem hydrochloride — A calcium channel blocking agent used as a coronary vasodilator, an antiarrhythmic, and antihypertensive. * * * dil·ti·a·zem hy·dro·chlo·ride (dil tiґə zəm) [USP] a calcium channel blocking agent that acts as a vasodilator …   Medical dictionary