defect

defect
An imperfection, malformation, dysfunction, or absence; an attribute of quality, in contrast with deficiency, which is an attribute of quantity. [L. deficio, pp. -fectus, to fail, to lack]
- aortic septal d., aorticopulmonary septal d. a small congenital opening between the aorta and pulmonary artery about 1 cm above the semilunar valves, e.g., aorticopulmonary window. SYN: aorticopulmonary window.
- atrial septal d. a congenital d. in the septum between the atria of the heart, due to failure of the foramen primum or secundum to close normally; may involve atrioventricular canal cushions; occasionally there is strong evidence of autosomal dominant inheritance [MIM*108800]. In varying degree, it is also a common feature of the autosomal recessive Ellis-van Creveld syndrome [MIM*225500] and the autosomal dominant Holt-Oram syndrome [MIM*142900].
- atrial ventricular canal d. a d. caused by deficient or absent septal tissue immediately above and below the normal level of the atrioventricular valves, including the region normally occupied by the A-V septum in hearts with two ventricles. The A-V valves are abnormal to a varying degree.
- birth d. d. present at birth; sometimes referred to as congenital d..
- coupling d. familial goiter.
- Eisenmenger d. SYN: Eisenmenger complex.
- endocardial cushion d. SYN: persistent atrioventricular canal.
- fibrous cortical d. a common 1 to 3 cm d. in the cortex of a bone, most commonly the lower femoral shaft of a child, filled with fibrous tissue. Nonosteogenic or nonossifying fibroma by convention refers to lesions greater than 3 cm in diameter. SEE ALSO: nonossifying fibroma. SYN: nonosteogenic fibroma.
- filling d. displacement of contrast medium by a space-occupying lesion in a radiographic study of a contrast-filled hollow viscus, such as a polyp on a barium enema; also applied to defects in the otherwise uniform distribution of radionuclide in an organ, such as a metastasis in the liver on a 99mTc-sulfur colloid scan.
- Gerbode d. a d. in the interventricular portion of the membranous septum, associated with a communication between the right ventricle and the right atrium through an abnormality in the tricuspid valve.
- iodotyrosine deiodinase d. familial goiter.
- luteal phase d. a condition characterized by inadequate secretion of progesterone during the luteal phase of the menstrual cycle, with resultant infertility; subnormal luteal function commonly attributed to abnormal pituitary gonadotropin secretion. SYN: luteal phase deficiency.
- metaphyseal fibrous cortical d. a small fibrous cortical d. located in the metaphysis of a long bone.
- organification d. familial goiter.
- osteoporotic marrow d. (os′te-o-po-ro′tik) focal osteoporotic bone marrow d. of the jaw; a focal radiolucent d. composed of normal marrow.
- postinfarction ventricular septal d. a d. developed in the ventricular septum resulting from rupture of an acute myocardial infarction.
- relative afferent pupillary d. relative afferent pupillary d..
- salt-losing d. renal tubular abnormality causing loss of sodium in the urine.
- ventricular septal d. a congenital d. in the septum (membranous or muscular) between the cardiac ventricles, usually resulting from failure of the spiral septum to close the interventricular foramen.

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de·fect 'dē-.fekt, di-' n a lack or deficiency of something necessary for adequacy in form or function <a hearing \defect>

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de·fect (deґfekt) an imperfection, failure, or absence.

Medical dictionary. 2011.

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  • defect — de·fect / dē ˌfekt, di fekt/ n: something or a lack of something that results in incompleteness, inadequacy, or imperfection: as a: a flaw in something (as a product) esp. that creates an unreasonable risk of harm in its normal use see also… …   Law dictionary

  • defect — DEFÉCT, Ă, defecţi, te, s.n., adj. 1. s.n. Lipsă, scădere, imperfecţiune materială, fizică sau morală; cusur, meteahnă, neajuns, beteşug, hibă. ♦ Deranjament, stricăciune care împiedică funcţionarea unei maşini, a unui aparat. ♦ Ceea ce nu este… …   Dicționar Român

  • Defect — Defect, defects, or defected may refer to: Geometry and physical sciences Defect (geometry), a characteristic of a polyhedron Topological defect Isoperimetric defect Crystallographic defect, a structural imperfection in a crystal Biology and… …   Wikipedia

  • Defect — De*fect , n. [L. defectus, fr. deficere, defectum, to desert, fail, be wanting; de + facere to make, do. See {Fact}, {Feat}, and cf. {Deficit}.] 1. Want or absence of something necessary for completeness or perfection; deficiency; opposed to… …   The Collaborative International Dictionary of English

  • defect — Ⅰ. defect [1] ► NOUN ▪ a shortcoming, imperfection, or lack. ORIGIN Latin defectus, from deficere desert or fail . Ⅱ. defect [2] ► VERB ▪ abandon one s country or cause in favour of an opposing one …   English terms dictionary

  • defect — [dē′fekt΄; ] also, and for v. always [, dē fekt′, difekt′] n. [ME < L defectus < deficere, to undo, fail < de , from + facere, to DO1] 1. lack of something necessary for completeness; deficiency; shortcoming 2. an imperfection or… …   English World dictionary

  • Defect — De*fect , v. t. To injure; to damage. None can my life defect. [R.] Troubles of Q. Elizabeth (1639). [1913 Webster] …   The Collaborative International Dictionary of English

  • Defect — Defect, lat., mangelhaft; als Hauptwort D., Mangel, Gebrechen; defectiren, eine Rechnung untersuchen in Beziehung auf Rechnungsfehler; defectiv, was defect. – Defectbogen, im Buchhandel ein nachverlangter Bogen. – Defecte, in der Buchdruckerei… …   Herders Conversations-Lexikon

  • defect — (n.) early 15c., from M.Fr. defect and directly from L. defectus failure, revolt, falling away, from pp. of deficere to fail, desert (see DEFICIENT (Cf. deficient)). As a verb, from 1570s. Related: Defected; defecting …   Etymology dictionary

  • defect — [n] blemish, imperfection birthmark, blot, blotch, break, bug, catch, check, crack, deficiency, deformity, discoloration, drawback, error, failing, fault, flaw, foible, frailty, gap, glitch, gremlin, hole, infirmity, injury, irregularity, kink,… …   New thesaurus

  • Defect — De*fect , v. i. To fail; to become deficient. [Obs.] Defected honor. Warner. [1913 Webster] 2. to abandon one country or faction, and join another. [PJC] …   The Collaborative International Dictionary of English

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