sildenafil

sildenafil
A selective inhibitor of cGMP-specific phosphodiesterase type 5 (PDE5); relaxes the muscle in the penis, resulting in greater blood flow and erection; used to treat male impotence; potentiates the hypotensive effects of nitrates.

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sil·den·a·fil sil-'den-ə-.fil n a drug that is used in the form of its citrate C22H30N6O4S·C6H8O7 to treat erectile dysfunction in males, that by suppressing a phosphodiesterase enzyme also suppresses the enzyme's inhibitory effect on the hormone cyclic GMP, and that enables the cyclic GMP produced during sexual arousal to initiate the muscular and vascular changes which produce an erection see viagra

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n.
a drug administered orally for the treatment of erectile impotence. During sexual stimulation, it causes smooth muscle relaxation and increased blood flow to the corpus cavernosum of the penis, which results in erection. Side-effects include headache, facial flushing, dyspepsia, nasal congestion, and dizzinesss. Because of severe adverse reactions, the drug is contraindicated in patients taking nitrate-based drugs, such as glyceryl trinitrate. Trade name: Viagra.

Medical dictionary. 2011.

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Look at other dictionaries:

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  • Sildénafil — Général Nom IUPAC …   Wikipédia en Français

  • Sildenafil — Viagra redirects here. For other uses, see Viagra (disambiguation). Sildenafil …   Wikipedia

  • Sildenafil — Strukturformel Allgemeines Freiname Sildenafil …   Deutsch Wikipedia

  • sildenafil — /sɪlˈdɛnəfɪl/ (say sil denuhfil) noun a drug, sildenafil citrate, which improves sexual function in males …  

  • sildenafil — A drug used to treat erectile dysfunction. Sildenafil relaxes the smooth muscle of the penis to allow increased blood flow and erection. It is a type of phosphodiesterase inhibitor. Also called Viagra …   English dictionary of cancer terms

  • sildenafil —  ou sildénafil  n.m. Médicament contre les troubles de l érection …   Le dictionnaire des mots absents des autres dictionnaires

  • sildenafil — noun virility drug (trade name Viagra) used to treat erectile dysfunction in men • Syn: ↑sildenafil citrate, ↑Viagra • Usage Domain: ↑trade name (for: ↑Viagra) • Hypernyms: ↑ …   Useful english dictionary

  • Sildenafil-Citrat — Dieser Artikel oder Abschnitt ist nicht hinreichend mit Belegen (Literatur, Webseiten oder Einzelnachweisen) versehen. Die fraglichen Angaben werden daher möglicherweise demnächst gelöscht. Hilf Wikipedia, indem du die Angaben recherchierst und… …   Deutsch Wikipedia

  • sildenafil citrate — noun The citrate salt of sildenafil, marketed as Viagra, a treatment for erectile dysfunction …   Wiktionary

  • sildenafil citrate — noun virility drug (trade name Viagra) used to treat erectile dysfunction in men • Syn: ↑sildenafil, ↑Viagra • Usage Domain: ↑trade name (for: ↑Viagra) • Hypernyms: ↑ …   Useful english dictionary

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