ankyrin

ankyrin
An erythrocyte membranal protein that binds spectrin. A deficiency in a. may lead to a type of hereditary spherocytosis. SYN: anchorin, syndein. [G. ankyra, anchor, + -in]

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an·ky·rin (angґkə-rin) a membrane protein of erythrocytes and brain that anchors spectrin to the plasma membrane at the sites of anion channels. Defects of ankyrin lead to elliptocytosis, spherocytosis, and pyropoikilocytosis.

Medical dictionary. 2011.

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  • Ankyrin — protein Name = ANK1, erythrocytic caption = Ribbon diagram of a fragment of the membrane binding domain of ankyrin R. From PDB|1N11. width = 250 HGNCid = 492 Symbol = ANK1 AltSymbols = AnkyrinR, Band2.1 EntrezGene = 286 OMIM = 182900 RefSeq = NM… …   Wikipedia

  • Ankyrin — Die Struktur eines Teils der membranbindenden Struktur von Ankyrin Ankyrine sind Repeat Proteine, die wie Antikörper zu den Bindungsproteinen gehören. Ankyrine sind Cytoskelett Proteine, die über dynamische, nicht kovalente Bindungen mit… …   Deutsch Wikipedia

  • Ankyrin repeat — The ankyrin repeat is a 33 residue motif in proteins consisting of two alpha helices separated by loops, first discovered in signaling proteins in yeast Cdc10 and Drosophila Notch. Ankyrin repeats mediate protein protein interactions and are… …   Wikipedia

  • Ankyrin deficiency — Known also as hereditary spherocytosis (HS), this is a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice (yellowing) and splenomegaly (enlargement of the spleen), due to deficiency of ankyrin, a protein… …   Medical dictionary

  • ankyrin — Globular protein (200 kD) that links spectrin and an integral membrane protein (Band III) in the erythrocyte plasma membrane. Isoforms exist in other cell types …   Dictionary of molecular biology

  • ankyrin — noun Any of a family of adaptor proteins that mediate the attachment of integral membrane proteins to the spectrin actin based membrane skeleton …   Wiktionary

  • ankyrin — …   Useful english dictionary

  • ankyrin repeat — See ANK repeat …   Dictionary of molecular biology

  • Deficiency, ankyrin — Known also as hereditary spherocytosis (HS), this is a genetic disorder of the red blood cell membrane clinically characterized by anemia, jaundice (yellowing) and splenomegaly (enlargement of the spleen), due to deficiency of ankyrin, a protein… …   Medical dictionary

  • ANK — ankyrin …   Medical dictionary

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