leucovorin calcium


leucovorin calcium
[USP] the calcium salt of folinic acid, used as an antidote for folic acid antagonists, e.g., methotrexate, when there is need to reverse the toxic effects of the latter, in the treatment of megaloblastic anemias due to folic acid deficiency, and as an adjunct in the palliative treatment of colorectal carcinoma; administered orally, intramuscularly, or intravenously.

Medical dictionary. 2011.

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  • Calcium — A mineral found mainly in the hard part of bones. Bones serve as a storage area for calcium. Calcium is added to bones by cells called osteoblasts. It is removed from bones by cells called osteoclasts. When children consume calcium, they absorb… …   Medical dictionary

  • Leucovorin — Strukturformel Allgemeines Freiname Leucovorin Andere Namen Folinsäure …   Deutsch Wikipedia

  • leucovorin — SYN: folinic acid. l. calcium the calcium salt of l. (folinic acid); used to counteract toxic effects of folic acid antagonists, for the treatment of megaloblastic anemias, and as an adjunct to cyanocobalamin in pernicious anemia. SY …   Medical dictionary

  • leucovorin — lüˈkävərə̇n noun ( s) Etymology: leuco (from New Latin Leuconostoc, genus name of Leuconostoc citrovorum) + vor (from New Latin citrovorum, specific epithet of Leuconostoc citrovorum) + in more …   Useful english dictionary

  • Fluorouracil — Systematic (IUPAC) name 5 fluoro 1H pyrimidine 2,4 d …   Wikipedia

  • folinic acid — 1. The active form of folic acid that acts as a formyl group carrier in transformylation reactions; the calcium salt, leucovorin calcium, has therapeutic use. 2. The term is occasionally applied to other folates. SYN: citrovorum factor …   Medical dictionary

  • Folinic acid — Systematic (IUPAC) name (2S) 2 {[4 [(2 amino 5 formyl 4 oxo 5,6,7,8 tetrahydro 1H pteridin 6 yl)methylamino] benzoyl]amino}pentanedioic acid Clinical data …   Wikipedia

  • Лейковорин кальция — Действующее вещество ›› Кальция фолинат* (Calcium folinate*) Латинское название Leucovorin calcium АТХ: ›› V03AF03 Кальция фолинат Фармакологические группы: Витамины и витаминоподобные средства ›› Детоксицирующие средства, включая антидоты Состав …   Словарь медицинских препаратов

  • Wellcovorin — Well·co·vo·rin (wel″ko voґrin) trademark for preparations of leucovorin calcium …   Medical dictionary

  • Colorectal cancer — Classification and external resources Diagram of the lower gastrointestinal tract ICD 10 C …   Wikipedia