calmodulin


calmodulin
A small, ubiquitous eukaryotic protein that binds calcium ions, thereby becoming the agent for many of the cellular effects long ascribed to calcium ions. This calcium-protein complex binds to the apoenzyme, to form the holoenzyme, of certain phosphodiesterases; through these, or other as yet unknown mechanisms, the complex regulates adenylate and guanylate cyclase s, many kinases, phospholipase A2 activity, and other basic cellular functions. [calcium + modulate]

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cal·mod·u·lin .kal-'mäj-ə-lən n a calcium-binding protein that mediates cellular metabolic processes (as muscle-fiber contraction) by regulating the activity of specific calcium-dependent enzymes

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cal·mod·u·lin (kal-modґu-lin) a ubiquitous calcium-binding protein of eukaryotic cells that mediates a variety of cellular responses to calcium. The calcium-calmodulin complex acts as a messenger, affecting the activity of many enzymes and nonenzyme proteins, including the calcium pump, numerous specific protein kinases and cyclic nucleotide phosphodiesterases, spectrin, histones, and tubulin.

Medical dictionary. 2011.

Look at other dictionaries:

  • Calmodulin 1 — (phosphorylase kinase, delta) PDB rendering based on 1a29 …   Wikipedia

  • Calmodulin — Vorhandene Strukturdaten: s. UniProt Masse/Länge …   Deutsch Wikipedia

  • Calmodulin — Calmodulin, in allen Eukaryotenzellen vorhandenes, calciumbindendes Protein, das als Ca2+ Calmodulin Komplex verschiedene Enzyme aktiviert und so in das Stoffwechselgeschehen der Zelle eingreift …   Deutsch wörterbuch der biologie

  • calmodulin — calmodulin. См. кальмодулин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • calmodulin — [kal mä′jo͞o lin΄, kal mä′jəlin΄] n. [ CAL(CIUM) + MODUL(ATE) + IN1] a protein in nearly all cells that binds to calcium and regulates many important cell functions, as nerve impulse transmissions and muscle action …   English World dictionary

  • Calmodulin — [ http://www.pdb.org/pdb/static.do?p=education discussion/molecule of the month/pdb44 1.html more details...] ] Calmodulin (CaM) (an abbreviation for CALcium MODULated proteIN) is a calcium binding protein expressed in all eukaryotic cells. It… …   Wikipedia

  • Calmodulin — Cal|mo|du|lin [Kurzw. aus ↑ Calcium u. Modulation; ↑ in (3)], das; s, e: ein Protein aus 148 Aminosäuren, das als intrazellulärer Rezeptor für Calcium Ionen zahlreiche Ca abhängige Stoffwechselprozesse im Organismus steuert. * * * Calmodulin  … …   Universal-Lexikon

  • calmodulin — noun Etymology: calcium + modulate + 1 in Date: 1978 a calcium binding protein that mediates cellular metabolic processes (as the contraction of muscle fibers) by regulating the activity of calcium dependent enzymes …   New Collegiate Dictionary

  • calmodulin — Ubiquitous and highly conserved calcium binding protein (17 kD) with four EF hand binding sites for calcium (3 in yeast). Ancestor of troponin C, leiotonin C, and parvalbumin …   Dictionary of molecular biology

  • calmodulin — /kal moj euh lin/, n. Biochem. a calcium binding protein occurring in many tissues and participating in the regulation of many biochemical and physiological processes. [1975 80; CAL(CIUM) + MODUL(ATE) + IN2] * * * …   Universalium


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