myospherulosis

myospherulosis
A chronic granulomatous reaction to undetermined spherical structures frequently contained within a microscopic cyst; first reported in cystic lesions in skeletal muscle from eastern Africa and subsequently in nasal infections in the U.S. [myo- + L. sphaerula, small sphere, + G. -osis, condition]

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myo·spher·u·lo·sis (mi″o-sfēr″u-loґsis) an inflammatory giant cell reaction linked to topical use of tetracycline in oil-based ointment on wounds.

Medical dictionary. 2011.

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  • Myospherulosis — Placement of topical tetracycline in a petrolatum base into a surgical site may occasionally result in a unique foreign body reaction, known as myospherulosis. The resultant histopathologic pattern is most unusual and initially was mistakenly… …   Wikipedia

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