Purine


Purine
One of the two classes of bases in DNA and RNA. The purine bases are guanine (G) and adenine (A). Uric acid, the offending substance in gout, is a purine end-product.
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The parent substance of adenine, guanine, and other naturally occurring p. “bases”; not known to exist as such in mammals.
- p.-nucleoside phosphorylase a ribosyltransferase that reversibly catalyzes the phosphorolysis of a p. nucleoside with orthophosphate to produce a p. and α-d-ribose 1-phosphate; an inherited deficiency of this enzyme leads to cellular immunodeficiency.

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pu·rine 'pyu̇(ə)r-.ēn n
1) a crystalline base C5H4N4 that is the parent of compounds of the uric-acid group
2) a derivative of purine esp a base (as adenine or guanine) that is a constituent of DNA or RNA

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n.
a nitrogen-containing compound with a two-ring molecular structure. Examples of purines are adenine and guanine, which form the nucleotide of nucleic acids, and uric acid, which is the end-product of purine metabolism.

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pu·rine (puґrēn) [L. purum pure + urine] a heterocyclic compound, C5H4N4, which is not found free in nature, but is variously substituted to produce a group of compounds known as purines or purine bases (see illustration under base), of which uric acid is a metabolic end product. The purine bases include adenine and guanine, which are constituents of nucleic acids, and hypoxanthine and xanthine.

Medical dictionary. 2011.

Look at other dictionaries:

  • Purine — Structure et représentation de la 9H Purine ou (3H imidazo)[4,5 d]pyrimidine Général …   Wikipédia en Français

  • purine — [ pyrin ] n. f. • 1904; all. Purin, dér. sav. du rad. du lat. purus « pur » et de urique ♦ Biochim. Substance azotée basique dont la structure comporte deux chaînes fermées (l une à 5, l autre à 6 atomes). ● purine nom féminin Composé… …   Encyclopédie Universelle

  • purine — [pyoor′ēn΄, pyoor′in] n. [Ger purin < L purus, pure + ModL uricum, uric acid + in, INE3] 1. a colorless, crystalline organic compound, C5H4N4, the parent substance of the uric acid group of compounds 2. any of several basic substances produced …   English World dictionary

  • purine — purine. См. пурин. (Источник: «Англо русский толковый словарь генетических терминов». Арефьев В.А., Лисовенко Л.А., Москва: Изд во ВНИРО, 1995 г.) …   Молекулярная биология и генетика. Толковый словарь.

  • purine — 1898, from Ger. purin, said to be from L. purum “pure” (see PURE (Cf. pure)) + Mod.L. uricum “uric acid” + chemical suffix INE (Cf. ine) (2) …   Etymology dictionary

  • Purine — chembox ImageFile=Purine chemical structure.png ImageSize= 345px ImageFile2= IUPACName=7H purine OtherNames= Section1= Chembox Identifiers CASNo=120 73 0 PubChem=1044 ChemSpiderID = 1015 SMILES=C1=C2C(=NC=N1)N=CN2 MeSHName=Purine Section2=… …   Wikipedia

  • Purine — Strukturformel Allgemeines Name Purin Andere Namen 3,5,7 Triazaindol 7H Imidazo(4,5 d)pyrimidin …   Deutsch Wikipedia

  • purine — /pyoor een, in/, n. Chem., Biochem. 1. a white, crystalline compound, C5H4N4, from which is derived a group of compounds including uric acid, xanthine, and caffeine. 2. one of several purine derivatives, esp. the bases adenine and guanine, which… …   Universalium

  • purine — noun Etymology: German Purin, from Latin purus pure + New Latin uricus uric (from English uric) + German in 2 ine Date: 1898 1. a crystalline base C5H4N4 that is the parent of compounds of the uric acid group 2. a derivative of purine; especially …   New Collegiate Dictionary

  • purine — (pu rin) A basic, heterocyclic, nitrogen containing molecule with two joined rings that occurs in nucleic acids and other cell constituents; most purines are oxy or amino derivatives of the purine skeleton. The most important purines are adenine… …   Dictionary of microbiology


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