colistin

colistin
A mixture of cyclic polypeptide antibiotics from a strain of Bacillus polymyxa; separable into polymyxins. SYN: colimycin.
- c. sulfate the sulfate salt of an antibacterial substance produced by the growth of a strain of Bacillus polymyxa, consisting primarily of c. A with small amounts of c. B; it is effective against most Gram-negative bacteria (except Proteus); given orally for intestinal antibacterial action. SEE ALSO: colistimethate sodium, polymyxin.
- c. sulfomethate sodium SYN: colistimethate sodium.

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co·lis·tin kə-'lis-tən, kō- n a polymyxin produced by a bacterium of the genus Bacillus (B. polymyxa var. colistinus) and used against some gram-negative pathogens esp. of the genera Pseudomonas, Escherichia, Klebsiella, and Shigella

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n.
an antibiotic administered by mouth to sterilize the bowel before surgery. Colistin is a mixture of antimicrobial substances produced by a strain of the bacterium Bacillus polymyxa. Trade name: Colomycin.

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co·lis·tin (ko-lisґtin) a polypeptide antibiotic of the polymyxin (q.v.) group, produced by the growth of the soil bacterium Bacillus polymyxa var. colistinus, specifically effective against many gram-negative bacteria, especially Pseudomonas aeruginosa, but also useful against others, including Escherichia coli and species of Klebsiella, Shigella, and Brucella; Proteus species are resistant.

Medical dictionary. 2011.

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  • Colistin — Systematic (IUPAC) name N (4 amino 1 (1 (4 amino 1 oxo 1 (3,12,23 tris(2 aminoethyl) 20 (1 hydroxyethyl) 6,9 diisobutyl 2,5,8,11,14,19,22 heptaoxo 1,4,7,10,13,18 hexaazacyclotricosan 15 ylamino)butan 2 ylamino) 3 hydroxybutan 2 ylamino) 1… …   Wikipedia

  • Colistin — Strukturformel Allgemeines Freiname Colistin Andere Namen …   Deutsch Wikipedia

  • colistin — n. an antibiotic used mainly to sterilize the bowel before surgery; it is taken by mouth. Colistin is a mixture of antimicrobial substances produced by a strain of the bacterium Bacillus polymyxa. Trade names: Colomycin …   The new mediacal dictionary

  • colistin sulfate — [USP] the sulfate salt of colistin, used in the treatment of various systemic, urinary tract, gastrointestinal, ophthalmic, and otic infections due to gram negative bacteria; administered orally, parenterally, and topically …   Medical dictionary

  • colistin — noun Etymology: New Latin colistinus, specific epithet of the bacterium producing it Date: 1951 a polymyxin produced by a bacterium (Bacillus polymyxa var. colistinus) from Japanese soil …   New Collegiate Dictionary

  • colistin — /keuh lis tin/, n. Pharm. a toxic antibiotic polypeptide, C45H85O10N13, produced by the bacterium Bacillus colistinus, used in sulfate form against a broad spectrum of microorganisms and in the treatment of severe gastroenteritis. [1950 55; < NL… …   Universalium

  • colistin — noun A polymixin antibiotic effective against a range of gram negative bacteria …   Wiktionary

  • colistin — co·lis·tin …   English syllables

  • colistin — co•lis•tin [[t]kəˈlɪs tɪn[/t]] n. pha a broad spectrum antibiotic derived from the soil bacterium Bacillus colistinus, used esp. for treating gastroenteritis • Etymology: 1950–55; < NL colistinus epithet for a variety of Bacillus polymyxa …   From formal English to slang

  • colistin — kəˈlistə̇n, kō noun ( s) Etymology: colist (from New Latin colistinus, specific epithet of the bacterium producing it) + in : a polymyxin antibiotic produced by a bacterium of the genus Bacillus (B. polymyxa var. colistinus) and used against some …   Useful english dictionary

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