iduronate
- i. sulfatase an enzyme required for the desulfation of 2-sulfate i. residues in heparan sulfate. It is also required in dermatan sulfate degradation; Hunter syndrome is associated with a deficiency of this enzyme.

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idu·ron·ate (i″du-ronґāt) a salt, ester, or anionic form of iduronic acid.

Medical dictionary. 2011.

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  • Iduronate-2-sulfatase — is a sulfatase enzyme associated with Hunter syndrome. PBB Summary section title = summary text = Iduronate 2 sulfatase is required for the lysosomal degradation of heparan sulfate and dermatan sulfate. Mutations in this X chromosome gene that… …   Wikipedia

  • iduronate-2-sulfatase — idu·ron·ate 2 sul·fa·tase (i″du ronґāt sulґfə tās) [EC 3.1.6.13] a lysosomal enzyme of the hydrolase class that catalyzes the cleavage of sulfate groups from the L iduronate residues of dermatan sulfate and heparan sulfate, a …   Medical dictionary

  • UDP-iduronate — UDP id·uron·ate (īd″u ronґāt) a nucleotide derivative of iduronate, synthesized from UDP glucuronate; it donates iduronate groups in proteoglycan synthesis …   Medical dictionary

  • IDS — iduronate sulfatase; immune deficiency state; infectious diseases service; inhibitor of DNA synthesis; integrated delivery system; International Documentation System; intraduodenal stimulation; Inventory for Depressive Symptomatology;… …   Medical dictionary

  • IDS — • iduronate sulfatase; • immune deficiency state; • infectious diseases service; • inhibitor of DNA synthesis; • integrated delivery system; • International Documentation System; • intraduodenal stimulation; • Inventory for Depressive… …   Dictionary of medical acronyms & abbreviations

  • Hunter syndrome — Classification and external resources ICD 10 E76.1 ICD 9 277.5 …   Wikipedia

  • Mucopolysaccharidosis — MPS I redirects here. For zhuyin or bopomofo, a phonetic system for romanizing Chinese, also known as Mandarin Phonetic Symbols I, see Bopomofo. Mucopolysaccharidosis Classification and external resources ICD 10 E76 ICD 9 …   Wikipedia

  • Hunter syndrome — A genetic metabolic disorder that arises from deficiency of the enzyme iduronate sulfatase, resulting in tissue deposits of molecules called mucopolysaccharides. The characteristic features of Hunter syndrome include dwarfism, bone deformities, a …   Medical dictionary

  • Sulfatase — Pfam box Symbol = Sulfatase Name = width =200 caption =Steryl sulfatase Pfam= PF00884 InterPro= IPR000917 SMART= PROSITE = PDOC00117 SCOP = 1auk TCDB = OPM family= 24 OPM protein= 1p49 PDB=PDB3|1fsu :43 486 PDB3|1hdhB:3 501 PDB3|1p49A:25… …   Wikipedia

  • Arylsulfatase B — Crystallographic structure of putative tetrameric arylsulfatase from Escherichia coli.[1] Identifiers …   Wikipedia

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